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If the pills don’t work or aren’t safe for you to take, your doctor may prescribe a drug called alprostadil. It helps boost blood flow to the penis, triggering an erection within minutes.

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The study protocol was approved by the Ethical Review Committee of the School of Pharmacy, University of Gondar, Ethiopia with an approval number of SoP 826/09. Before the data collection, the purpose of the study and the proceedings were provided to each study participant and verbal consent was obtained. No personal identifiers were included in the questionnaire and confidentiality of the information was assured in such a way that no disclosure of the collected data was made apart from the study purpose.
National Center for Complementary and Alternative Medicine: "Aromatherapy May Make Good Scents, But Does It Work?" .

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Half of men with diabetes will experience ED within 10 years of their diagnosis. High blood sugar levels can damage the nerves that control sexual stimulation. They can also damage the blood vessels needed to provide adequate blood flow to the penis in order to have and maintain an erection.
The Prostate Cancer Prevention Trial was a landmark study by Thompson et al that prospectively assessed the time to developing CVD after the diagnosis of ED. There were 4247 men with no ED at study entry; 2420 developed incident ED (defined as the first report of ED of any grade) over 5 years. Those men that developed ED had a 1.45-fold higher probability of experiencing a CV event compared with men who did not develop ED.27

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These exercises, when combined into a regimen that you do on a daily basis, help strengthen the muscles that are used to achieve and maintain an erection. Pharmaceuticals are always going to be popular, but if you set aside some time everyday for the above erectile dysfunction exercises, you will targeting the root cause of the problem and improving your chances of better erectile health.
Trazodone. This is an antidepressant. It’s still uncertain whether it works for ED. It’s not recommended.

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No. You should never take two types of ED medication at the same time as it could lead to a dangerous overdose.

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Self injection into the penis may be performed a maximum of two to three times per week. Never more than once in any 24 hour period.

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    There are contraindications for each drug (i.e., reasons why a person should not try to use it). Men with certain liver, kidney, or cardiovascular conditions may not be able to take ED medications safely. Men taking nitrates and alpha-blockers to treat hypertension may need to find other ways to treat their ED. Other health conditions could make PDE-5 medications unsafe for men.

    You shouldn’t take these pills if you take nitrate drugs for heart disease. Doing so can cause a dangerous drop in blood pressure.
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    To see an improvement in erectile dysfunction, one research paper recommended that those experiencing ED engage in aerobic exercise “of moderate to vigorous intensity 4 times per week for 40 minutes”.

    Follow your doctor’s instructions when taking ED medicine. Usually, a man takes 1 tablet 30 minutes to 1 hour before he plans to have sex. Sildenafil works for 4-8 hours; vardenafil works for up to 8 hours; and tadalafil works for up to 36 hours.
    Checking the penis for sensitivity determines any nervous system origins. Inspection of penile appearance helps rule out Peyronie's disease. A blood pressure check rules out circulation problems by checking wrist and ankle pulse.

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    Steege, J. F., Stout, A. L. & Carsen, C. C. (1986) Patient satisfaction in Scot and Small carrion penile implant recipients: a study of 52 patients. Archives of Sexual Behaviour, 15, 393–399.CrossRefGoogle Scholar

    Doing a few of these exercises every day, if not all, can prevent erectile dysfunction. Considering the sedentary and stressful lives of youngsters today, Vidyut recommends men even as young as 20 years old to practise these exercises to protect themselves from this crippling condition. AskMen India shares 6 exercises from Vidyut Jammwal’s kalari sutra workout that improve sexual health:
    General good health, particular cardiovascular, is important for sexual function. Three exercises that may be particularly helpful are pelvic floor exercises, aerobic exercise, and anaerobic exercise.

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    Dr Gautam Banga, consultant and andrologist at the Sunrise Hospital New Delhi previously told indianexpress.com that in India, ED is a taboo because people don’t see it as a medical disorder but as sexual incompetence. “It does not happen because the man is not interested in or is incapable of having sex, but there are medical reasons like diabetes, high cholesterol, high blood pressure and ischemic heart disease (IHD), depression etc., that leads to ED,” he said.

    Health care professionals and especially pharmacists should counsel sildenafil users on how and when to use the medication and the common side effects associated with the drug. Users should also be aware of the impact of using sildenafil concomitantly with other illicit drugs and advised to use it when it is only necessary to avoid its addiction and minimize adverse effects. The regulatory body should control the availability of sildenafil and other PDE5Is in places other than pharmacies, monitor the sale of prescription-only medications on an OTC basis, and monitor their utilization.
    Research in stem cell therapy and gene therapy for erectile dysfunction is also ongoing. Penis Curved When Erect Could I have CAD? Treat Bent Fingers Treat HR+, HER2- MBC Tired of Dandruff? Life with Cancer Cuzin, B. "Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience." Ther Adv Urol 8.4 Aug. 2016: 249-256. Diamond, L.E., et al. "Co-administration of Low Doses of Intranasal PT-141, a Melanocortin Receptor Agonist, and Sildenafil to Men With Erectile Dysfunction Results in an Enhanced Erectile Response." Urology 65 (2005): 755. Jackson G., et al. "The second Princeton consensus on sexual dysfunction and cardiac risk: new guidelines for sexual medicine." Journal of Sexual Medicine 3 (2006): 28. Kim, E.D. "Erectile Dysfunction Treatment & Management." Medscape.com. Oct. 12, 2015. Matz, E.L., et al. "Stem cell therapy for erectile dysfunction." Sex Med Rev 2018 April 6 epub ahead of print. United States. Food and Drug Administration. "Hidden Risks of Erectile Dysfunction 'Treatments' Sold Online." Mar. 23, 2015. Yafi, F.A., et al. "Erectile dysfunction." Nat Rev Dis Primers 2 (2016): 16003.

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There is growing interest in SWT and other regenerative therapies that seek to "cure" ED, rather than simply treat it. Although some early data support this line of research, there is a lack of high-quality evidence supporting the widespread use of SWT (or other treatments like plasma-rich protein or stem cell injections) for treatment of ED. In the absence of clinical trials showing its long-term effectiveness, SWT has not been approved by the FDA for treatment of ED and is not covered by insurance. In its guidelines for ED treatment, the AUA designates SWT as an "investigational" treatment that should be limited to research trials. "Our results show that real-world practice does not adhere to these recommendations," Drs. Weinberger, Eleswarapu, and colleagues write. They believe that patients exploring treatment for ED "should be evaluated by urologists who are equipped to conduct a formal men's health evaluation and provide a data-driven and patient-centric discussion of treatment options."

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There are four FDA-approved prescription medications to treat erectile dysfunction: Sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra).

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Exercise is good for the circulatory system. It keeps blood flowing smoothly throughout the body.

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These exercises, when combined into a regimen that you do on a daily basis, help strengthen the muscles that are used to achieve and maintain an erection. Pharmaceuticals are always going to be popular, but if you set aside some time everyday for the above erectile dysfunction exercises, you will targeting the root cause of the problem and improving your chances of better erectile health.

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