Erectile dysfunction related to medical/physical causes is often treatable but less commonly curable. In some cases of medication-induced erectile dysfunction, changes in medication may improve erections. Similarly, in men with a history of arterial trauma, surgical intervention can restore erectile dysfunction. In most cases of ED associated with a medical condition, treatment allows one to have an erection "on demand" or with the aid of medications/device (but not spontaneous).
The most common cause of ED is a lack of flowing blood to erectile tissue. Plaque and damaged vessels can restrict circulation enough to disrupt function. Typically, symptoms begin with difficulty maintaining an erection before advancing to a complete inability to obtain one.
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If you continue having difficulty maintaining an erection after committing to a healthier lifestyle, make an appointment with your doctor. They can do tests to assess if you have an underlying health condition and prescribe medications to help you achieve firmer, healthier erections.
If an individual is taking ketoconazole, erythromycin, or ritonavir, it is recommended that the maximum dose of avanafil not exceed 50 mg in 24 hours.
Methods: A facility-based cross-sectional study was conducted from March 20, 2017 to May 10, 2017, among male clients who visited community pharmacies in Gondar town, North West Ethiopia. A self-administered, structured questionnaire was used to collect data from Sildenafil users older than 18 years, that started using the drug (Sildenafil) for at least 6 months before the data collection period. A regression analysis was conducted to determine the association between study variables, and a P-value of <0.05 was considered to declare statistical significance.
Step 2. Specialist Phone Consultation (Free) – Once the specialist has reviewed the medical records and approved your case, we will present options and pricing, at which point we will also offer a free phone consultation to discuss questions and concerns.
In the present study, the recreational use of sildenafil was also more prevalent in participants who had multiple sexual partners. Similar findings were also reported in a study conducted in Brazil (6), and this could be because men with multiple sexual partners may be attempting to impress their partners with prolonged sexual periods (7, 8). It could also be attributed to a low level of self-esteem in men who had multiple sexual partners.
Recently, the US Food and Drug Administration (FDA) has issued a safety announcement regarding TRT. In part it reads ‘The benefit and safety of these medications have not been established. We are also requiring these manufacturers to add information to the labeling about a possible increased risk of heart attacks and strokes in patients taking testosterone.’37
Finally, there are NO-releasing polymers that are capable of delivering NO in a pharmacologically useful way. Such compounds include compounds that release NO upon being metabolised and compounds that release NO spontaneously in aqueous solution. Initial animal studies suggest that cavernosal injections of NO polymers can significantly improve erectile function.48
Journal of Urology: “Chapter 1: The management of erectile dysfunction: an AUA update.”
First line treatment will be medication with a phosphodiesterase inhibitor such as sildenafil (Viagra), tadalafil (Cialis) or avanafil (Spedra). These drugs only work when used together with sexual stimulation and will have no effect on your sex drive. There is no evidence that these drugs are dangerous if you have underlying heart disease. However, they should not be used if you are taking nitrates (e.g. GTN, isosorbide) for angina
Pharmalogic TreatmentPharmacologic options for treatment of ED include oral phosphodiesterase type 5 inhibitors (PDE5Is) or intraurethral or intracavernosal injection alprostadil.6 Intracavernosal nonprostaglandin agents such as papaverine, phentolamine, and atropine have also been used to successfully manage ED, but none are FDA-approved for this indication. Testosterone replacement may also be considered for men with hypogonadism.6
Erection problems usually produce a significant psychological and emotional reaction in most men. This is often described as a pattern of anxiety, low self-esteem, and stress that can further interfere with normal sexual performance. This "performance anxiety" needs to be recognized and addressed by your health care provider.
These include oral medications such as Viagra, Sildenafil, Cialis, Tadalafil, Levitra and Spedra. The most effective treatment will vary from person to person.
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